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Chapter 36.Mood Stabilizers

Edited by:
    https://doi.org/10.1176/appi.books.9781615374809.md36

    Sections

    Lithium | Valproate | Carbamazepine | Oxcarbazepine | Lamotrigine | Gabapentin | Pregabalin | Topiramate | Suicide and Mood Stabilizers | Future Directions | References

    Excerpt

    Lithium was used more than 50 years ago to treat “manic-depressive” illness in children (Annell 1969). Since then, a variety of potentially mood-stabilizing agents have been used to treat psychiatric disorders in children and adolescents. Mood stabilizers can be divided into the older, traditional agents, including lithium, valproate, and carbamazepine, and the newer agents, including the anticonvulsants oxcarbazepine, lamotrigine, gabapentin, pregabalin, and topiramate (López-Muñoz et al. 2018). The use of anticonvulsants migrated from pediatric neurology to child psychiatry after clinicians noticed their mood and behavioral effects.

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