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Sections

Definition | Clinical Description | Epidemiology | Comorbidity | Etiology, Mechanisms, and Risk Factors | Age at Onset, Course, and Prognosis | Evaluation | Differential Diagnosis | Treatment | References

Excerpt

Typical onset of bipolar disorder occurs from puberty and into early adulthood. In various editions of DSM, the diagnostic criteria have fluctuated between broader and narrower approaches, reflecting a tension between being more inclusive and being more precise and predictive. The DSM-5 criteria (American Psychiatric Association 2013) represent an effort toward being more restrictive. The changing bipolar disorder criteria from one DSM edition to the next and the broad or narrow definitions used by different investigators are not superimposable. These differences may have a direct bearing on the understanding of the condition’s etiology, biological markers, and treatment response.

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