Chapter 22.Huntington’s Disease
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Excerpt
There are few examples of a condition that defines neuropsychiatric illness and care as clearly as Huntington’s disease (HD). This heritable disease produces neurodegeneration within frontal-subcortical circuits that manifests as motor, cognitive, emotional, and behavioral symptoms and signs, making it a paradigmatic neuropsychiatric disorder. The individual and family with HD present an opportunity for clinicians with neuropsychiatric training to fully use their expertise and existing treatments to alleviate suffering, even in the absence of a definitive cure for HD itself. Research in HD is advancing quickly, and, as of this writing, several symptomatic and disease-modifying therapies are being studied for the condition.
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