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Epidemiology | Clinical Features and Presentation | Outcomes | Risk Factors and Prevention | Detection and Recognition | Pathophysiology and Neurobiology | Clinical Evaluation and Management | Conclusion | References

Excerpt

Delirium has been recognized for thousands of years. The origins of the word trace back to the Latin delirare, literally meaning to “go off the furrow” (de “off, away from” + lira “earth thrown up between two furrows”) and metaphorically referring to a state of deviation or derangement. As early as 500 b.c., the terms phrenitis and delirium were used to denote mental changes associated with fever, head trauma, or poisoning. Hippocrates’ writings reference phrenitis and lethargus to distinguish between what are now recognized as the two major subtypes of delirium, hyperactive and hypoactive, respectively. Formalized diagnostic criteria were eventually established and published in DSM-III (American Psychiatric Association 1980).

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